POTENTIAL ANTIDIABETIC OF TAMARIND WASTE: EFFECTS ON THE PANCREATIC -AMYLASE

Diabetes is a complex metabolic disease characterized by plasma hyperglycemia. One of theways treatment diabetes the inhibition pancreatic α-amylase. However, drugsavailable in market carry out range side effects. Therefore, present work aimed toevaluate effect tamarind waste (skin and seed) rejected food industry on theactivity Hydroethanolic extract (70%) skin seedwere prepared, lyophilized, used concentration curve α-amylase activity 3,5dinitro-salicylate assay. Kinetic analysis was performed simultaneously varying both substrate(starch) extracts. Statistical analyses were carried Scientist Program. Both extracts(skin reduced enzymatic dependence way. However,the seed reported bigger strength inhibition, as revealed IC 50 13,26 µg/mL,compared to 470,16 µg/mL for extract. Kinect studies showed that seedextract presented an parabolic non-competitive type (KI 1 10,07µg/mL e KI 2 10,37 µg/mL). Conversely, mixed linear 1615,78 411,01 We concluded waste, mainly extract,can be considered preparation with therapeutic potential management ofdiabetes.